Table 1.
Intraoperative outcomes in retrospective comparative studies concerning liver resection for hepatocellular carcinoma via laparoscopy or open approach
| Ref. | Laparoscopies (n) |
Median blood loss, mL |
Blood transfusion |
Median operative time, min |
||||||
| L | O | P value | L | O | P value | L | O | P value | ||
| Cheung et al[11], 2013 | 32 | 150 | 300 | 0.001 | 0% | 4.7% | NS | 204 | 232 | NS |
| Kanazawa et al[10], 2013 | 28 | 88 | 505 | 0.0003 | 0% | 4% | 0.0379 | 228 | 236 | NS |
| Lee et al[12], 2011 | 33 | 150 | 240 | NS | 6.1% | 10% | NS | 225 | 195 | 0.019 |
| Ker et al[46], 2011 | 116 | 139 | 1147 | < 0.001 | 6.9% | 50.9% | < 0.001 | 156 | 190 | NS |
| Hu et al[69], 2011 | 30 | 520 g | 480 g | NS | - | - | - | 180 | 170 | NS |
| Kim et al[70], 2011 | 26 | - | - | - | 19.2% | 24.1% | NS | 147 | 220 | 0.031 |
| Truant et al[13], 2011 | 36 | 452 | 447 | NS | 2.8% | 3.8% | NS | 193 | 215 | NS |
| Tranchart et al[9], 2010 | 42 | 364 | 723 | < 0.0001 | 9.5% | 16.7% | NS | 233 | 221 | NS |
| Aldrighetti et al[71], 2010 | 16 | 258 | 617 | 0.008 | 4% | 6% | NS | 150 | 240 | 0.044 |
| Belli et al[30], 2009 | 54 | 297 | 580 | < 0.01 | 11% | 25.6% | 0.03 | 167 | 185 | 0.012 |
| Lai et al[72], 2009 | 25 | - | - | - | - | - | - | 150 | 135 | NS |
| Endo et al[73], 2009 | 10 | - | - | NS | - | - | - | - | - | - |
| Sarpel et al[74], 2009 | 20 | - | - | - | - | - | NS | 161 | 165 | NS |
| Belli et al[48], 2007 | 23 | 260 | 377 | NS | 0% | 17.3% | 0.036 | 148 | 125 | 0.016 |
| Lee et al[75], 2007 | 25 | 100 | 250 | 0.012 | 4% | 0% | NS | 220 | 195 | NS |
| Kaneko et al[76], 2005 | 30 | 350 | 505 | NS | - | - | - | 182 | 210 | NS |
| Laurent et al[77], 2003 | 13 | 620 | 720 | NS | 4% | 28.6% | NS | 267 | 182 | 0.006 |
| Shimada et al[78], 2001 | 17 | 400 g | 800 g | NS | 5.9% | 10.5% | NS | 325 | 280 | NS |
L: Laparoscopy; O: Open; NS: Non significant.