Table 1.
Therapy | IBD patients with loss of response, side effects, hypersensitivity (n = 6) | Control IBD patients (n = 1) |
Mean age at diagnosis, yr | 34.9 (17-67) | 36.4 (17-66) |
Mean disease duration at biological therapy, yr | 7.1 (1-20) | 7.7 (1-21) |
CD/UC | 19/17 | 17/14 |
Male/female | 14/22 | 14/17 |
Previous biological therapy | 22 | 15 |
Concomitant steroid therapy | 5 | 3 |
Concomitant thiopurine therapy | 18 | 16 |
Previous surgery | 16 | 7 |
Active disease | 25 | 0 |
CD: Crohn’s disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease.