Table 2.
Sensitivity and specificity of 18F-FDG PET for the diagnosis of cardiac sarcoidosis
Study | Year | Number of patients | Cohort | Diagnosis | Sensitivity (%) | Specificity (%) |
---|---|---|---|---|---|---|
Yamagishi | 2003 | 17 | Cardiac sarcoid | histologic | 100 | n/a |
Okumura | 2004 | 22 | Sarcoid | histologic | 100 | 91 |
Ishimaru | 2005 | 32 | Sarcoid | clinical | 100 | 82 |
Ohira | 2008 | 21 | Suspected cardiac sarcoid | ECG and Holter diagnosis | 88 | 39 |
Langah | 2009 | 65 | Suspected cardiac sarcoid | suspected sarcoid | 85 | 90 |
Weighted Mean | 168 | 89.9 | 81.4 | |||
Mean | 168 | 91 | 75.5 |
All studies with 18 F-FDG PET against gold standard of Japanese Ministry Guidelines. (Adapted with permission from: Ohira H, Tsujino I, Yoshinaga K. (1) F-Fluoro-2-deoxyglucose positron emission tomography in cardiac sarcoidosis. Eur J Nucl Med Mol Imaging. 2011;38:1773–83 [48••]