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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2013 Sep 27;134:123–127. doi: 10.1016/j.drugalcdep.2013.09.017

Figure 2.

Figure 2

Event-related EEG (ERSP) following juvenile saline (white) or ketamine (black) exposure assessed at 7 weeks (juvenile) and 12 weeks (adult). Figure 2A shows event-related theta (4 to 12 Hz), while figure 2B shows event-related gamma (30 to 80 Hz). Ketamine treatment reduced event-related theta at both the juvenile and adult time points. Saline-treated mice showed an age related decrease in theta over the timespan of the ages assessed here. Likewise, saline-treated mice showed an age dependent increase in event-related gamma, which appeared to be blocked in ketamine-treated mice, suggesting that ketamine treatment in juvenile mice blocked normal maturation of event-related gamma. Asterisk shows significance at p>0.05.