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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2013 Sep 27;134:123–127. doi: 10.1016/j.drugalcdep.2013.09.017

Figure 3.

Figure 3

Event Related Potential following juvenile saline (white) or ketamine (black) exposure assessed at 7 weeks (juvenile) and 12 weeks (adult). Figure 3A shows the P20 component of the ERP, while figure 3B shows the N40 response. Saline-treated mice showed an age dependent increase in the P20 component, which appeared to be blocked in ketamine-treated mice, suggesting that ketamine treatment in juvenile mice blocked normal maturation of this response. Ketamine treatment reduced amplitude of the N40 component of the ERP at both the juvenile and adult time points. Saline-treated mice showed an age related decrease in N40 over the timespan of the ages assessed here. Asterisk shows significance at p>0.05.