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. Author manuscript; available in PMC: 2015 May 28.
Published in final edited form as: J Control Release. 2014 Mar 15;0:90–96. doi: 10.1016/j.jconrel.2014.03.016

Fig. 6.

Fig. 6

Evans Blue staining of mice to determine tumor vessel leakiness. Single intravenous injection was performed for each treatment with the GMP dose at 16 mg/kg and Cisplatin at 1.6 mg/kg. Twenty-four hours later, mice were injected with 100 mg/kg of Evans blue. After 30 min, the mice were sacrificed, and samples from the tumors were removed. The concentration of Evans Blue was then determined spectrophotometrically. Results are shown as the mean weight of Evans Blue per gram tissue. * p <0.05 vs. Control; # p<0.05 vs. Combo NP. n=3.