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Transcriptional and translational up-regulation of Adm. A: Quantitative RT-PCR analysis of Adm from wild-type and Admhi/hi tissues (n = 3–10) at 4 months of age. B: Peptide levels of AM from 2- to 3-month-old wild-type and Admhi/hi lung and kidney as determined by a radioimmunoassay (n = 5–6). C: Plasma levels of AM from 4-month-old wild-type and Admhi/hi animals using a fluorescent immunoassay (n = 3). All values are means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001
