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. Author manuscript; available in PMC: 2014 May 5.
Published in final edited form as: Dev Neurobiol. 2012 Apr;72(4):664–675. doi: 10.1002/dneu.20983

Figure 4.

Figure 4

The effects of DHT with and without an antimitotic agent (cis-platin) on LM expression and muscle fiber type in laryngeal explant cultures 10 days in vitro. (A) Explanted larynges cultured in the absence of androgen did not express LM. (B) Ten days of androgen treatment increased LM mRNA expression. (C) However, inclusion of cis-platin along with DHT in the media prevented the increase in LM mRNA. (D) Explanted larynges cultured in the absence of androgen maintain typical juvenile patterns of acid stable ATPase activity in muscle fibers. (E) Androgen treatment for 10 days changed the ATPase staining pattern: fibers were uniformly light and small dark fibers were not present. (F) In the presence of cis-platin and DHT, fiber type ATPase staining resembled the untreated control (D).