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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Nat Immunol. 2013 Dec 8;15(2):152–160. doi: 10.1038/ni.2784

Figure 6.

Figure 6

ATF3 mediates much of the transcriptional response to HDL treatment of macrophages. a–b, Microarray and ChIP-Seq analysis of WT and Atf3-deficient BMDMs pre-treated with HDL (2 mg/ml) for 6 h and subsequently stimulated for 4 h with CpG (100 nM) or P3C (50 ng/ml). a Schematic representation of the model used to identify ATF3 target genes (also see Methods). b Visualization of transcripts induced (left panel) or repressed (right panel) by CpG. At least three biological replicates per condition were generated.