Fig. (1).

RY, MK, AT and GC disparity curves reveal oriC locations in bacterial and archaeal genomes. Z-curves show a single oriC in the genome of the bacterium of Cyanothece sp. PCC 7425 (A) and one, two, three oriCs in genomes of the archaea of Pyrococcus abyssi GE5 (B), Halobacterium sp. NRC-1 (C), and Sulfolobus acidocaldarius DSM 639 (D), respectively. Note that the Z-curves have been drawn for the rotated sequences beginning and ending in the maximum of the GC disparity curves. Short vertical line indicates dnaA or cdc6 gene location, and short up vertical arrow indicates the identified oriC location.