. 2011 Feb 4;32(2):167–174. doi: 10.1038/aps.2010.191

Table 1. The survival time values for normothermic rats, vehicle-treated rats, and KYNA-treated rats. Data were mean±SD. n=6. ^bP<0.05, in comparison with group 1; ^eP<0.05, in comparison with group 2.

Treatment groups	Survival time (min)
Normothermic rats	480±5
Vehicle-treated heatstroke rats	89±6^b
KYNA (10 mg/kg, iv)-treated heatstroke rats	152±7^e
KYNA (30 mg/kg, iv)-treated heatstroke rats	191±9^e
KYNA (100 mg/kg, iv)-treated heatstroke rats	356±17^e

All heatstroke rats which had heat exposure (43 °C) were withdrawn exactly at 68 min and then allowed to recover at room temperature (26 °C). Heatstroke rats were killed 85 min after the start of heat stress, where as the normothermic rats were killed about 480 min after the start of experiment (or at the experiment end). Vehicle or KYNA was injected 4 h before the start of experiments.

Table 1. The survival time values for normothermic rats, vehicle-treated rats, and KYNA-treated rats. Data were mean±SD. n=6. bP<0.05, in comparison with group 1; eP<0.05, in comparison with group 2.

Table 1. The survival time values for normothermic rats, vehicle-treated rats, and KYNA-treated rats. Data were mean±SD. n=6. ^bP<0.05, in comparison with group 1; ^eP<0.05, in comparison with group 2.