Table 3.

Fold change of some of the metabolites with age

Metabolite	Fold change*
	2–4 yrs	5–12 yrs
Acetone	−0.31	−2.34
Succinate	−1.33	−1.95
Betaine/TMAO	−1.49	−1.86
Creatinine	+0.32	+2.34
Creatine	+4.3	−3.7
Glycine	−0.58	−2.50
Citrate	−0.50	−2.45

^*Fold change relative to 0–1 yr age group. Negative sign indicates decrease with age and the positive sign indicates increase with age.