Table 2.
| Characteristic | Classic | Exertional |
|---|---|---|
| Health condition | Predisposing factors | Healthy |
| Age | Elderly | Younger |
| Conditions | High environmental temp | Occurs sporadically |
| Sweating | Usually absent | Present |
| Activity | Sedentary | Strenuous |
| Disseminated intravascular coagulation | Mild | Marked |
| Acute renal failure | <5% patients | 25–30% patients |
| Lactic acidosis | Rare | Common |
| Hyperuricemia | Moderate | Severe |
| Hypocalcemia | Rare | Common |
| Hypoglycaemia | Rare | Common |
| Hypokalemia | Rare | Common |
| Rhabdomyolysis | Rare | Common |
| CPK | Mildly elevated | Marked elevated |
| Mechanism | Poor dissipation of environmental heat | Excessive endogenous heat production |