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. Author manuscript; available in PMC: 2014 May 5.
Published in final edited form as: Nat Genet. 2013 Jun;45(6):580–585. doi: 10.1038/ng.2653

Figure 1.

Figure 1

Effect of sample size and MAF on power to detect eQTLs. (a) Power for cis-eQTL analysis in which we assume α = 0.05/200,000, reflecting Bonferroni correction for 200,000 hypotheses based on 20,000 genes and an average of 10 non-redundant SNPs in the region ±100 kb of each gene. (b) Power for trans-eQTL analysis in which we test 20,000 genes against 5 million SNPS in a total of 1 × 1011 tests with α = 5 × 10−13.