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Persistent ROS generation was induced by oridonin in HeLa cells. The cells were treated with 80 μmol/L oridonin for 1, 3, 6, 12, and 24 h, and the DCF-positive cells were measured by flow cytometric analysis. The corresponding linear diagram of the FACScan histograms was expressed at the bottom. n=3. Mean±SD. cP<0.01 vs control group.
