. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Cancer Chemother Pharmacol. 2014 Mar 12;73(5):991–997. doi: 10.1007/s00280-014-2432-x

Table 2.

Docetaxel pharmacokinetic parameters determined in 21 patients by compartmental analyses.

		AUC/D (h/L)	CL (L/hr)	CL (L/m²)	Vss (L)
Cycle 1	Mean	0.019	57.8	29.1	1160
	SD	0.005	20.5	11.2	865
	Median	0.020	51.1	25.28	811
	Range	0.008-0.029	33.9-120	18.2-61.9	380.22-3605

Cycle 2	Mean	0.016	67.3	33.8	1008
	SD	0.005	21.0	11.6	745
	Median	0.015	61.6	30.8	741
	Range	0.008-0.027	36.4-119.2	17.5-64.1	152-2937