Table 5.

Group Mean (S.E.) Female Neurotransmitter Levels (ng/mg protein)

REGION1		DA	DOPAC	HVA	DA TO	NE	5HT	HIAA
Frontal Cortex	0-NS	1.04 (.13) +	2.6 (.22) *	.66 (.11) #	.41 (.05)	16.4 (3.6)	41.8 (3.6) *+	2.6 (.12)
	0-PS	1.13 (.17)	2.48 (.26)	.42 (.1)	.49 (.09)	22 (3.9)	48.3 (5.3)	2.6 (.15)
	0.5-NS	.95 (.11)	2.02 (.08)	.51 (.13)	.47 (.05)	14.7 (3.5)	35.2 (2.3)	2.3 (.18)
	0.5-PS	1.05 (.14)	2.04 (.14)	.76 (.24)	.47 (.05)	15.8 (4.1)	39.3 (2.1)	2.6 (.08)
	2.5-NS	.8 (.16)	2.0 (.32)	.5 (.09)	.49 (.1)	14.8 (3.4)	32.7 (3)	2.3 (.18)
	2.5-PS	2.04 (.83)	2.43 (.18)	.46 (.08)	.82 (.33)	20.3 (4)	40.7 (3)	2.5 (.19)
Nucleus Accumb	0-NS	294.1 (20.2)	40.1 (3.1) #	21 (1.4) +#	.14 (.01)	17.1 (1.2) #	28 (4) +	15.5 (1.2) +~#
	0-PS	207.2 (31.9)	25 (5.6)	11.7 (2)	.12 (.02)	9.9 (1.4)	10.9 (2)	8.3 (1.5)
	0.5-NS	246.4 (30.1)	26.7 (2.4)	19.8 (2.2)	.12 (.01)	15.1 (1.2)	22.4 (3.7)	12.8 (1.6)
	0.5-PS	261 (37.3)	32.4 (4.5)	16.3 (1.9)	.13 (.01)	12.9 (1.9)	14.3 (1.7)	12.2 (1.8)
	2.5-NS	282.2 (34.6)	27.3 (2.8)	16.7 (1.6)	.1 (.007)	11.8 (1.8)	18.4 (1.9)	14.3 (2)
	2.5-PS	290.5 (30.5)	34.9 (3.6)	20 (2.2)	.13 (.02)	16.8 (2.3)	14.1 (1.4)	13.1 (1.6)
Striatum	0-NS	296 (27.5)	40.6 (4.2)	19.6 (1.3)	.14 (.02) #	20.9 (3.3)	16.4 (3.4) *	13.8 (1.2)
	0-PS	319 (26.2)	30.6 (2.2)	19.5 (0.6)	.1 (.01)	16.3 (1.3)	13.3 (1.5)	12.6 (.63)
	0.5-NS	347 (27.8)	35.7 (5)	19.5 (1.5)	.1 (.009)	18.3 (2.2)	21.1 (3.6)	15 (.89)
	0.5-PS	341 (27.6)	37.8 (4.4)	21.9 (1.4)	.11 (.007)	19.1 (1.7)	21.2 (2.5)	15.7 (1.1)
	2.5-NS	333 (32.3)	30.8 (4.4)	18.7 (1.1)	.1 (.012)	15.9 (.81)	13.7 (1.8)	15.7 (1.6)
	2.5-PS	265 (30)	29.6 (1.8)	17.3 (0.7)	.12 (.01)	16.8 (1.18)	10.1 (.69)	13.9 (1.1)
Hipp	0-NS	.23 (.17)	2.33 (.24) #		.04 (.02)	20.3 (1.5) #	37.6 (3.3)	5.3 (.31)
	0-PS	.15 (.03)	2.6 (.21)		.07 (.02)	25.5 (2.7)	44.8 (5)	5.7 (.24)
	0.5-NS	.12 (.02)	2.56 (.21)		.05 (.01)	24.7 (2.3)	35.9 (4.7)	5.9 (.35)
	0.5-PS	.1 (.03)	1.85 (.15)		.046 (.01)	19.5 (1.15)	35.2 (4.3)	5.5 (.46)
	2.5-NS	.16 (.01)	2.4 (.2)		.066 (.01)	22.5 (1.03)	34.9 (3.4)	5.8 (.23)
	2.5-PS	.08 (.04)	2.23 (.15)		.03 (.01)	20.3 (2)	30.9 (24)	5.1 (.29)
Midbrain	0-NS	.85 (.08)	2.2 (.18)		2.72 (.23)	27.3 (1.2) +	41 (2.1) +~#	5.9 (.27) +~#
	0-PS	.83 (.08)	1.7 (.24)		2.33 (.41)	23.3 (1.8)	44.2 (3.7)	6.17 (.4)
	0.5-NS	.93 (.1)	1.9 (.25)		2.3 (.31)	26.1 (2)	46.2 (4.6)	7.3 (.53)
	0.5-PS	.8 (.1)	2 (.17)		2.9 (.39)	23.8 (1.6)	34.7 (2.4)	5.6 (.37)
	2.5-NS	.91 (.1)	2.1 (.38)		2.7 (.4)	29.1 (3.4)	48.2 (5.7)	6.2 (.7)
	2.5-PS	.75 (.04)	1.7 (.36)		1.7 (.19)	24.9 (3)	34.6 (5.2)	5.2 (.45)
Hypothal	0-NS	5.5 (.81)	2.49 (.12)		.51 (.05) *	66.1 (1.17)	68.1 (4) +~#	4.7 (.12) #
	0-PS	7.5 (.82)	2.75 (.15)		.4 (.038)	83.2 (8.1)	74.3 (2.5)	5.6 (.16)
	0.5-NS	8.2 (1.2)	2.64 (.09)		.38 (.05)	83.1 (7.3)	62.1 (3.2)	5.5 (.21)
	0.5-PS	7.5 (.83)	2.6 (.1)		.35 (.038)	75.6 (6.3)	67.7 (4.3)	5.8 (.26)
	2.5-NS	5.6 (.63)	2.68 (.15)		.51 (.05)	74.4 (7.8)	69.9 (3.5)	5.6 (.34)
	2.5-PS	6.2 (.93)	2.63 (.21)		.46 (.03)	70.4 (6.3)	59.8 (5.1)	5.2 (.24)
Olfactory Bulb	0-NS	1.14 (.1) ~#	4.81 (.34) #	1.21 (.06) #	4.36 (.3)	2.78 (.15)	18.1 (1.9) ~*	1.74 (.16) ~*
	0-PS	1.03 (.13)	4.5 (.47)	1.21 (.13)	4.6 (.55)	2.48 (.18)	16.4 (1.74)	1.72 (.11)
	0.5-NS	1.36 (.26)	5.7 (.65)	1.28 (.14)	4.6 (.41)	2.58 (.25)	13.2 (.74)	1.52 (.1)
	0.5-PS	.95 (.09)	4.56 (.41)	1.14 (.08)	4.9 (.27)	2.33 (.10)	14.7 (1.34)	1.5 (.08)
	2.5-NS	1.0 (.07)	4.06 (.37)	1.14 (.07)	4.13 (.32)	2.31 (.16)	17.1 (1.62)	1.86 (.12)
	2.5-PS	1.3 (.13)	5.55 (.48)	1.54 (.09)	4.33 (.28)	2.61 (.15)	15.38 (.93)	1.69 (.07)

¹Regions: Frontal Cortex, Nucleus Accumb=Nucleus Accumbens, Striatum, Hippo=Hippocampus, Midbrain, Hypothal=Hypothalamus, Olfactory Bulb

^*= significant effect of MeHg;

⁺= significant effect of PS;

^#significant interaction of MeHg×PS;

^~= marginal effect