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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Mar 3;38(5):1216–1226. doi: 10.1111/acer.12373

Figure 6.

Figure 6

High-cholesterol diet selectively impairs BK channel function. Reprsentative traces of arterial diameter of isolated, de-endothelialized and in vitro pressurized middle cerebral artery of rat on control (A) vs. high-cholesterol (B) diet. (C) Averaged constriction of de-endothelialized arteries in response to 1 µM paxilline and 0.8 mM 4-aminopirydine in control (n=5) vs. high-cholesterol diet group (n=4).*p<0.05, when compared to paxilline-induced constriction of the arteries from rats on control diet.