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. Author manuscript; available in PMC: 2014 May 5.
Published in final edited form as: Chemistry. 2013 Oct 14;19(47):15872–15878. doi: 10.1002/chem.201302188

Figure 2.

Figure 2

Selection of target conjugates for phosphorylated, phosphonated, and methylated tRNASec mimics that carry a hydrolysis-resistant adenosine-3′-amide linkage. Anticodon loop replacement with the U1A protein recognition sequence is highlighted by dashed boxes. Potential sites for enzymatic ligation with T4 RNA ligase are indicated by blue bars.