Table 1.
Numbers | Case | Control | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Author | Country | Ethnicity | Disease | Case | Control | Pro/Pro | Pro/Ala | Ala/Ala | Pro/Pro | Pro/Ala | Ala/Ala | Association pa | Power (%)b |
Cao, 2012 | China | East Asian | NAFLD | 169 | 699 | 159 | 10 | 0 | 656 | 43 | 0 | 0.910 | 83.7 |
Yang, 2012 | China | East Asian | NAFLD | 436 | 467 | 406 | 30 | 0 | 409 | 58 | 0 | 0.007 | 85.1 |
Rey, 2010 | Germany | European | NAFLD | 263 | 363 | 206 | 48 | 9 | 280 | 77 | 6 | 0.878 | 70.6 |
Dongiovanni, 2010 | Italy | European | NAFLD | 202 | 346 | 166 | 33 | 3 | 295 | 50 | 1 | 0.217 | 64.8 |
Qing, 2007 | China | East Asian | NAFLD | 155 | 141 | 142 | 13 | 0 | 130 | 11 | 0 | 0.857 | 40.5 |
Pan, 2009 | China | East Asian | RA | 421 | 207 | 411 | 10 | 0 | 190 | 17 | 0 | 0.002 | 70.7 |
El-Sohenmy, 2006 | China | East Asian | RA | 473 | 400 | 450 | 23 | 0 | 374 | 25 | 1 | 0.241 | 84.0 |
Bowes, 2012 | United Kingdom | European | PsA | 5712 | 932 | 4416 | 1216 | 80 | 747 | 174 | 11 | 0.058 | 100 |
Butt, 2006 | Canada | European | PsA | 251 | 235 | 208 | 41 | 2 | 177 | 51 | 7 | 0.017 | 59.7 |
Allelic association.
Assuming an odds ratio of 1.5 (small effect size) at a level of significance of 0.05.
HWE, Hardy–Weinberg equilibrium; NAFLD, nonalcoholic fatty liver disease; RA, rheumatoid arthritis; PsA, psoriatic arthritis.