Table 4.

Mean Differences in Body Composition Outcomes at Ages 60–64 Years by Lifetime Physical Activity Score^a, the MRC National Survey of Health and Development, 1946–2010

Lifetime Activity Score by Sex	No.	%	Fat Mass Indexb		Android (Abdominal):Gynoid (Hip) Fat Mass Ratio		Appendicular Lean Mass Indexc		Appendicular Lean Mass Index Adjusted for Fat Mass Index
			Mean Difference	95% CI	Mean Difference	95% CI	Mean Difference	95% CI	Mean Difference	95% CI
Men
Unadjusted
0–1	126	22.14	0	Referent	0	Referent	0.00	Referent		Referent
2–3	150	26.36	0.57	−0.28, 1.43	−1.39	−5.07, 2.28	0.04	−0.19, 0.26	−0.04	−0.23, 0.15
4–5	153	26.89	0.8	−0.05, 1.65	−0.59	−4.24, 3.07	0.18	−0.04, 0.40	0.07	−0.12, 0.27
6–8	140	24.60	−0.64	−1.50, 0.23	−4.68	−8.41, −0.95	0.14	−0.09, 0.36	0.22	0.02, 0.42
Ptrend			0.20d		0.03		0.12		0.01
P valuee			<0.001		0.93		0.2		0.7
Adjustedf
0–1	126	22.14	0.00	Referent	0.00	Referent	0	Referent	0	Referent
2–3	150	26.36	0.81	−0.04, 1.66	−0.59	−4.25, 3.06	0.06	−0.17, 0.28	−0.05	−0.24, 0.15
4–5	153	26.89	1.18	0.32, 2.04	0.87	−2.83, 4.57	0.26	0.03, 0.48	0.1	−0.09, 0.30
6–8	140	24.60	−0.2	−1.08, 0.68	−2.94	−6.72, 0.84	0.22	−0.01, 0.45	0.24	0.04, 0.44
Ptrend			0.75d		0.22		0.02		<0.01
P valuee			<0.001		0.94		0.17		0.75
Women
Unadjusted
0–1	153	23.83	0	Referent	0	Referent	0	Referent	0	Referent
2–3	197	30.69	−0.75	−1.80, 0.30	−2.05	−4.60, 0.50	−0.15	−0.34, 0.04	−0.06	−0.20, 0.08
4–5	151	23.52	−2.18	−3.30, −1.06	−1.9	−4.62, 0.81	−0.09	−0.29, 0.11	0.17	0.03, 0.32
6–8	141	21.96	−2.94	−4.08, −1.80	−4.72	−7.48, −1.95	−0.16	−0.37, 0.04	0.19	0.04, 0.34
Ptrend			<0.001		<0.01		0.2		<0.01d
Adjustedf
0–1	153	23.83	0	Referent	0	Referent	0	Referent	0	Referent
2–3	197	30.69	−0.51	−1.58, 0.55	−1.97	−4.56, 0.62	−0.15	−0.34, 0.04	−0.09	−0.23, 0.05
4–5	151	23.52	−1.89	−3.05, −0.74	−1.37	−4.18, 1.44	−0.11	−0.32, 0.09	0.12	−0.03, 0.27
6–8	141	21.96	−2.55	−3.72, −1.37	−4.1	−6.96, −1.24	−0.17	−0.38, 0.04	0.14	−0.02, 0.30
Ptrend			<0.001		0.01		0.17		0.01d

Abbreviations: CI, confidence interval; MRC, Medical Research Council.

^a Lifetime physical activity score derived by adding the physical activity measures at ages 36, 43, 53, and 60–64 years, from none-lowest (0–1) to highest (6–8) activity; activity at each age was coded as 0 for inactive (no participation), 1 for moderately active (participated 1–4 times), and 2 for most active (participated ≥5 times) in the previous month (at age 36 years) or in the previous month or 4-week period (at ages 43, 53, and 60–64 years).

^b Fat mass index is calculated as weight (kg)/height (m)^1.2.

^c Appendicular lean mass index is calculated as appendicular lean mass (kg)/height (m)².

^d Evidence for departure from linearity (P < 0.05).

^e P value for sex interaction term.

^f Paternal occupational class when subject was 4 years of age, own educational attainment at age 26 years, and long-term limiting illness or disability at ages 60–64 years.