Concentration-dependent effects of vecuronium on adult muscle-type acetylcholine receptors expressed in HEK293 cells. (A) Tracing represent raw currents observed during the application of acetylcholine (ACh; 10 μmol/L for 1 s), either alone or in combination with 0.1, 1, 10, 100, and 1000 nmol/L vecuronium (VEC). (B) Concentration-response effect for vecuronium for inhibition of acetylcholine (10 μmol/L)-induced inward currents mediated by adult muscle-type acetylcholine receptor. Data points show the mean±SD (error bars) of 5 HEK293 cells.