Table 2. Drug-related adverse events reported during single-dose iv administration of hemoporfin in the studied healthy Chinese subjects.
| Subject No | Dose (mg/kg) | Gender | Drug-related adverse events reported |
|---|---|---|---|
| 101 | 2.5 | M | ALT concentration increased |
| 202 | 5 | M | ALP concentration increased |
| 301 | 7.5 | M | ALT concentration increased |
| 305 | 7.5 | M | ALT concentration increased |
| 307 | 7.5 | F | Nausea and abdominal pain |
| 310 | 7.5 | F | Abdominal pain |
| 402 | 10 | M | Upset stomach |
| 404 | 10 | F | Nausea |
| 405 | 10 | F | Upset stomach |
| 406 | 10 | F | Nausea and vomiting |
F, female; M, male.