Table 1. Effect of high cholesterol diet and OVX on weight, total cholesterol (TC), triglycerides (TG), calcium (Ca), phosphorus (P), ALP, osteocalcin (BGP), carboxy-terminal collagen crosslinks (CTX), estrogen (E2), and bone mineral density (BMD) level. Data are presented as the mean±SD. bP<0.05 vs Normal group.
| Normal (n=10) | High cholesterol fed rats (n=12) | OVX rats (n=12) | |
|---|---|---|---|
| Weight (g) | 311.00±21.95 | 439.17±65.76b | 320.83±28.87 |
| TC (mmol/L) | 1.87±0.39 | 3.17±1.06b | 2.04±0.7 |
| TG (mmol/L) | 0.76±0.17 | 0.58±0.18 | 0.71±0.26 |
| Ca (mmol/L) | 2.40±0.15 | 2.47±0.19 | 2.38±0.26 |
| P (mmol/L) | 4.16±2.13 | 4.47±1.68 | 4.64±1.98 |
| ALP (U/100 mL) | 16.15±0.68 | 12.34±0.46b | 20.41±0.71b |
| BGP (ng/mL) | 500.79±120.51 | 331.40±124.78b | 754.87±222.34b |
| CTX (ng/mL) | 62.49±31.31 | 85.55±30.82b | 95.77±36.96b |
| E2 (ng/L) | 4.44±0.33 | 4.54±0.39 | 4.05±0.31b |
| Femur BMD | 0.15±0.012 | 0.12±0.014b | 0.12±0.02b |
| Lumbar vertebrae BMD | 0.13±0.03 | 0.14±0.008 | 0.13±0.011 |