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. 2011 Oct 31;32(12):1498–1504. doi: 10.1038/aps.2011.135

Table 2. The expression of bone formation-related genes in the two groups.

Gene name Gene symbol High cholesterol fed rats OVX rats
Insulin-like growth factor binding protein 5 Igfbp5 −7.1 −3.1
Procollagen, Type XII, Alpha 1 Col12a1 −6.3 −4.3
Matrix metallopeptidase 8 Mmp8 −4.8 −2.5
Core binding factor beta Cbfb −4.6 −2.4
Caveolin Cav −4.6 −3.7
Transforming growth factor, beta receptor II Tgfbr2 −4.0 −4.2
Leptin receptor Lepr −4.0 −2.1
Wingless-type MMTV integration site 5A Wnt5a −3.8 −1.0
Bone morphogenetic protein 6 Bmp6 −3.8 −1.4
MAD homolog 6 (Drosophila) Smad6 −3.8 −1.2
Osteoglycin Ogn −3.7 −1.9
Bone morphogenic protein receptor, type II Bmpr2 −3.7 −2.9
MAD homolog 7 Smad7 −3.7 −2.2
Transforming growth factor, beta receptor III Tgfbr3 −3.7 −3.2
Insulin-like growth factor binding protein 7 Igfbp7 −3.1 −1.0
Catenin (Cadherin Associated Protein), beta 1 Ctnnb1 −3.1 −1.4
CD276 antigen Cd276 −3.1 −3.1
Parathyroid hormone receptor 2 Pthr2 −2.9 −1.4
Fibroblast growth factor receptor 2 Fgfr2 −2.9 −1.2
Fibroblast growth factor 9 Fgf9 −2.9 −0.8
Calcitonin receptor Calcr −2.8 −2.6
MAD homolog 4 (Drosophila) Smad4 −2.7 −1.1
Fibroblast growth factor 5 Fgf5 −2.5 −3.7
Procollagen, Type III, Alpha 1 Col3a1 −2.5 −0.8
MAD homolog 9 (Drosophila) Smad9 −2.3 −0.1
Matrix metallopeptidase 7 Mmp7 −2.3 −3.0
3-Hydroxy-3-methylglutaryl-coenzyme A reductase Hmgcr −2.3 −1.0
MAD homolog 5 (Drosophila) Smad5 −2.2 −2.0
Interleukin 6 signal transducer Il6st −2.2 −1.7
Fibroblast growth factor 8 Fgf8 −2.1 −0.7
Apolipoprotein E Apoe −2.0 −1.4
Procollagen, Type I, Alpha 2 Col1a2 −1.8 −0.4
Cbp/P300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 Cited1 2.1 0.9
Interleukin 6 IL6 2.2 3.0
Interferon beta 1 Ifnb1 3.1 1.3
Advanced glycosylation end product-specific receptor Ager 4.6 4.2