Table 4. Blood biochemical measurements in isoflurane-sedated rabbits. Mean±SD. n=6. bP<0.05 when compared with pretreatment (0 h) values. eP<0.05 when compared with the same time-point values in Group P.
| Variable | Time (h) |
Reference range | |||
|---|---|---|---|---|---|
| 0 | 12 | 24 | 30–36 | ||
| Creatinine (μmol/L) | 72.2±5.6 | 61.1±6.2b | 50.0±7.8be | 38.9±5.6be | 70–120 |
| GOT (U/L) | 5.5±2.0 | 25.0±3.3 | 35.5±3.0 | 31.5±6.0 | <30 |
| GPT (U/L) | 41.2±4.8 | 45.0±3.2 | 42.2±1.1 | 46.0±9.1 | <5–47 |
| LDH (U/L) | 236.5±90.5 | 241.1±76.6 | 253.3±152.2 | 201.1±92.1 | 243±50 |
| Total protein (g/L) | 59.1±6.1 | 40.1±18.2 | 31.1±9.0be | 41.0±4.1e | 54–75 |
| Albumins (g/L) | 40.0±2.0 | 26.1±10.1b | 23.1±11.2b | 25.2±2.0be | 27–50 |
| Total bilirubin (μmol/L) | 15.1±2.0 | 14.4±8.6 | 25.0±8.3 | 27.8±12.1 | <26 |
| Direct bilirubin (μmol/L) | 5.1±0.5 | 4.2±0.8 | 5.9±1.1 | 6.2±1.2 | <7 |
| Cholesterol (mmol/L) | 2.6±0.6 | 1.9±0.4 | 2.3±1.2 | 3.9±1.1 | <5.2 |
| Triglycerides (mmol/L) | 2.6±0.5 | 3.1±0.6 | 2.8±1.1 | 1.8±1.0 | <2.0 |
| CK (IU/L) | 1032.2±226 | 3468.1±7965b | 3548.2±1263be | 3108.3±3746be | 50–1300 |
CK, creatine kinase; LDH, lactate dehydrogenase; GOT, glutamic oxaloacetic transaminase; GST, glutamic pyruvic transaminase.