Table 2. Pharmacokinetic parameters for dexamethasone.
Parameters | Definitions | Values (% RSE) | BSV (% RSE) |
---|---|---|---|
CL/F (mL·kg−1·h−1) | Clearance | 172.7 (6.70) | – |
Q/F (mL·kg−1·h−1) | Inter-compartmental clearance | 14.32 (36.52) | 0.655 (36.66) |
Vc/F (mL/kg) | Central volume | 657.4 (12.55) | – |
Vp/F (mL/kg) | Peripheral volume | 263.2 (31.95) | – |
T0 (h) | The duration of the zero-order absorption | 10.47 (6.36) | – |
BSV, between subject variability; RSE, relative standard error.