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. 2012 Jan 3;33(1):127–136. doi: 10.1038/aps.2011.161

Table 4. Pharmacodynamic parameters for CYP3A1 and CYP3A2 protein after DEX administration.

Parameters Definitions Values (% RSE)
ksyn,1 (pmol·h−1·mg−1 protein)/(attomol mRNA·μg−1 total RNA) Synthesis rate for CYP3A1 protein 0.0359 (18.68)
kdeg,1 (h−1) Degradation rate for CYP3A1 protein 0.0268 (15.99)
m1 Amplification factor for CYP3A1 protein 0.911 (3.99)
ksyn,2 (pmol·h−1·mg−1 protein)/(attomol mRNA·μg−1 total RNA) Synthesis rate for CYP3A2 protein 0.486 (11.77)
kdeg,2 (h−1) Degradation rate for CYP3A2 protein 0.0567 (11.79)
m2 Amplification factor for CYP3A2 protein 0.287 (9.68)

RSE, relative standard error.