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. 2014 Apr 8;53(16):2672–2679. doi: 10.1021/bi500267c

Table 1. Kinetic Parameters for the Kinetic Mechanism in Scheme 4a.

k1 6.0 mM–1 s–1 (4.9–7.1)
k2 33 mM–1 s–1 (26–62)
kH2O 0.52 s–1 (0.43–0.62)
a

Values for the rate constants were determined globally with KinTek Explorer and the data from Figures 1 and 3. The values in parentheses are the confidence intervals reported by FitSpace at a X2 threshold of 1.4, that is, the change in the value that results in an increase in X2 of 40% if all of the other parameters are allowed to vary to improve the fit.