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Metabolism of 17β-estradiol to 17β-estradiol-3-glucuronide using UGT1A1-containing microsomal preparations from various cells.
| Microsomes | Turnover values (nmol· min−1· nmol−1 UGT1A1) |
|---|---|
| Supersomes | 2.04 ± 0.25 |
| Caco-2 | 2.15 ± 0.31 |
| HeLa | 3.41 ± 0.40 |
| MCF-7 | 2.50 ± 0.28 |
| HepG2 | 2.86 ± 0.33 |
