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. Author manuscript; available in PMC: 2014 May 5.
Published in final edited form as: Cancer Res. 2012 Dec 7;72(24):6490–6501. doi: 10.1158/0008-5472.CAN-12-1653

Fig. 2.

Fig. 2

Characteristics of tumors. mRNA level of ERα, PR, and Her2 in (A)tumor biopsies taken prior to OVX (n=34 tumors) and (B)tumors during OVX-induced weight gain, under high energy excess conditions (~27kcal/day excess). (C)Levels of ERα and PR in tumors measured with IHC (n=12-19 tumors/group). (D-E)Representative images of PR and Ki67 immunostaining, with insets showing normal duct as positive control; Bar = 25μm.(F)Quantification of Ki67 staining. (G)Representative western blot showing PR−A predominance in mammary tumors; uterus and T47D cells as positive controls. (H-J)Quantification of in vivo uptake of glucose(3H-2DOG) and dietary fat (14C-oleate/14C-palmitate), and FASN expression in PR+ and PR− tumors under low (~9kcal/day excess) or high (~27kcal/day excess) energy excess (n=55 tumors). (*p<0.05)