Table 1. Growth inhibition of MPSP-001 against various human cancer cell lines.
| Origin | Cell lines | IC50 (μmol/L) |
|---|---|---|
| Hepatocellular carcinoma | HepG2 | 9.1±4.2 |
| Acute monocytic leukemia | THP-1 | 1.9±1.2 |
| Chronic myelogenous leukemia | K562 | 6.9±3.9 |
| Gastric carcinoma | HGC-27 | 15.7±2.6 |
| Ovarian carcinoma | SKOV3 | 11.6±4.1 |
| Pancreatic carcinoma | PANC-1 | 15.4±6.6 |
| Colon adenocarcinoma | SW480 | 15.1±3.5 |
| Cervical carcinoma | Kba | 8.4±2.9 |
| Cervical carcinoma | HeLa | 8.1±3.3 |
| Lung adenocarcinoma | A549 | 15.0±5.8 |
| Breast carcinoma | MDA-MB-453 | 14.8±4.5 |
| Breast adenocarcinoma | MCF-7 | 12.4±2.7 |
Each value represents the mean±SD of three independent experiments.
aThe KB cell line was originally derived from an epidermal carcinoma of the mouth but has now been shown to have HeLa characteristics.