Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The effect of Sirt1 overexpression on TNF-α-induced IkBα degradation (A) and NF-κB activation (B). Control or Sirt1-overexpressing osteoblastic cells were treated with TNF-α (5.0 ng/mL) for 1 h. Activity of NF-κB was analyzed by luciferase reporter assay. bP<0.05 vs Ad-lacZ cells. eP<0.05 vs TNF-α-treated Ad-lacZ cells.
