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. 2012 Apr 30;33(5):691–700. doi: 10.1038/aps.2012.24

Figure 4.

Figure 4

U0126 and PD98059 inhibit invasion and migration of Bel-7402 cells induced by Shh. (A) Representative photographs (400×magnification) of Bel-7402 cells treated with or without U0126 for 24 h after being pretreated by Shh from a representative experiment. (B) Representative photographs (400×magnification) of Bel-7402 cells treated with or without PD98059 for 24 h after being pretreated by Shh from a representative experiment. (C) The numbers of Bel-7402 cells in the lower chamber in Figure 4A and 4B, each bar represents the mean±SD of three separate experiments. (D) Values of wound-healing assessed by measuring the pixel of wound area, each bar represents the mean±SD of three separate experiments. bP<0.05, cP<0.01 vs control; eP<0.05, fP<0.01 vs Shh.