Table 4. Associations between the Myostatin polymorphisms and haplotypes and obesity-related phenotypes in the male-offspring nuclear families (using QTDT).

	rs2293284	+2278G>A	rs3791783	Haplotype AGG	Haplotype AAA	Haplotype TGG
Tests of population stratification
Arms FM	0.8369	0.8863	0.5231	0.0380	0.2941	0.8020
Legs FM	0.8770	0.6429	0.2073	0.1628	0.3308	0.9252
Trunk FM	0.8360	0.9887	0.4130	0.2095	0.9978	0.6234
Total FM	0.6361	0.7558	0.3065	0.0366	0.1704	0.6735
Arms LM	0.8434	0.3007	0.6973	0.2123	0.9965	0.9340
Legs LM	0.8565	0.8388	0.3404	0.1911	0.3654	0.6376
Trunk LM	0.9700	0.3212	0.5018	0.5890	0.6590	0.1432
Total LM	0.8543	0.4315	0.6170	0.3543	0.4873	0.3508
PFM	0.5920	0.7613	0.1565	0.0748	0.3228	0.5666
BMI	0.4997	0.8251	0.8770	0.3337	0.6569	0.7534
Tests of total association
Arms FM	0.3257	0.9983	0.7203	0.2177	0.8140	0.4036
Legs FM	0.4830	0.7070	0.4520	0.1241	0.9067	0.6460
Trunk FM	0.7110	0.9008	9e-011	1e-010	1e-010	1e-010
Total FM	0.5192	0.7586	0.4999	0.1939	0.7371	0.5938
Arms LM	0.3248	0.4647	0.8148	0.5211	0.4268	0.2989
Legs LM	0.9976	0.6983	0.6973	0.9987	0.9875	0.9943
Trunk LM	0.9669	0.8866	0.2653	0.1344	0.8042	0.9428
Total LM	0.8674	0.7421	0.4502	0.3334	0.7260	0.8909
PFM	0.6581	0.7086	0.3939	0.1882	0.9170	0.7340
BMI	0.7354	0.5902	0.2277	0.0992	0.9181	0.8823
Tests of within-family association
Arms FM	0.3723	0.8014	0.5204	0.4385	0.3696	0.4379
Legs FM	0.5077	0.7687	0.9215	0.8879	0.4126	0.8352
Trunk FM	0.9999	0.7539	9e-011	1e-010	8e-011	1e-010
Total FM	0.3393	0.8366	0.6002	0.4447	0.2328	0.4987
Arms LM	0.5708	0.7574	0.5859	0.1714	0.5647	0.4864
Legs LM	0.9889	0.6936	0.5266	0.6683	0.9856	0.9932
Trunk LM	0.6566	0.6374	0.8479	0.1633	0.9004	0.2888
Total LM	0.8131	0.6397	0.6402	0.1784	0.8205	0.4546
PFM	0.4922	0.9674	0.7037	0.6164	0.4471	0.5206
BMI	0.4514	0.9527	0.4671	0.1114	0.7364	0.8398
1000 permutations of within-family association
Trunk FM	0.9463	0.7889	9e-011	1e-010	8e-011	1e-010

Obesity-related phenotype values are adjusted for age as a covariate. Bold values indicate significant P values (P<0.01).