Table 3. Effects of tiopronin on liver lipid content in rat fed with high fat diet. n=10. Mean±SD. cP<0.01 vs normal diet. eP<0.05, fP<0.01 vs high fat. TG, triglyceride; TC, total cholesterol; FFA, free fatty acids.
| Groups | Dose (mg/kg) | Liver |
||
|---|---|---|---|---|
| TG (mmol/g liver weight) | TG (mmol/g liver weight) | FFA (mmol/g liver weight) | ||
| Normal diet | – | 1.49±0.09 | 0.24±0.03 | 0.50±0.05 |
| High fat | – | 2.29±0.16c | 1.16±0.18c | 1.47±0.10c |
| High fat+tiopronin | 20 | 1.64±0.16e | 0.95±0.14e | 1.05±0.87f |
| High fat+UDCA | 15 | 2.06±0.32 | 0.93±0.19e | 1.37±0.11e |