Table 5. Average histological grades of steatosis, inflammation and mitochondrial surface area in rat fed with high fat diet. n=10. Mean±SD. cP<0.01 vs normal diet. eP<0.05, fP<0.01 vs high fat.
| Parameter | Normal diet | High fat | High fat+tiopronin | High fat+UDCA |
|---|---|---|---|---|
| Steatosis | 1.00±0.00 | 3.77±0.43c | 1.96±0.28f | 3.24±0.45 |
| Inflammation | 0 | 1.80±0.29c | 0.57±0.27f | 1.55±0.25 |
| Mitochondrial area (μm2) | 0.31±0.02 | 0.91±0.04c | 0.54±0.04f | 0.73±0.04f |