Table 1. Comparative activation and inactivation parameters of WT (at 30 μmol/L) and ΔKPQ (at 100 μmol/L) I_Na,P in the absence (control) and presence of 18β-GA. Mean±SD. n=6 per group. ^bP<0.05 vs control.

	WT				ΔKPQ
	Activation		Inactivation		Activation		Inactivation
	V1/2	K	V1/2	K	V1/2	K	V1/2	K
Control	−33.8±1.8	6.7±1.6	−81.8±0.4	7.2±0.3	−36.2±1.8	7.0±1.5	−75.1±0.4	4.8±0.4
18β-GA	−25.1±1.9b	7.7±1.7	−88.1±0.3b	6.9±0.2b	−28.6±1.6b	7.8±1.3b	−80.5±0.5b	5.1±0.4
Washout	−31.6±1.7	7.6±1.5	−83.0±0.4	7.2±0.4	−33.2±1.8	7.0±1.5	−75.4±0.4	4.7±0.4