Table 5. Levetiracetam pharmacokinetic parameters from the published literature and from our study.

Dose	Parameters	Fountain25	Pellock12	Chhun18	Our study
10 mg/kg, bid	C12 h (mg/L)	8.4±3.8	–	6.4±2.7	11.25±3.10
	t1/2 (h)	4.9±0.6	–	6.8±1.5	8.13±0.3
	CL/F (mg·kg−1·min−1)	1.14±0.18	–	1.24±0.29	0.69±0.1
20 mg/kg, bid	C12 h (mg/L)	15.6±5.3	–	12.7±4.7	17.5±2.63
	t1/2 (h)	4.9±0.4	6.0±1.1	6.8±1.5	8.13±0.22
	CL/F (mg·kg−1·min−1)	1.10±0.16	1.43±0.36	1.24±0.29	0.69±0.13
30 mg/kg, bid	C12 h (mg/L)	20.6±5.8	–	19.1±7.2	31.25±3.8
	t1/2 (h)	4.9±0.7	–	6.8±1.5	8.13±0.35
	CL/F (mg·kg−1·min−1)	1.12±0.119	–	1.24±0.29	0.69±0.09

CL/F, apparent oral clearance; t_1/2, elimination half-life.