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. 2012 Apr 30;33(6):737–742. doi: 10.1038/aps.2012.35

Table 1. Effect of β-asarone on cell viability and MMP in OGD/R treated PC12 cells.

Groups n Cell viability (OD value)
Normal control 10 0.79±0.04
Model control 10 0.46±0.02c
Nimodipine (10 μmol/L) 10 0.74±0.04f
β-asarone (20 μg/mL) 10 0.64±0.07c,f
β-asarone (30 μg/mL) 10 0.75±0.09f
β-asarone (45 μg/mL) 10 0.56±0.08c,f

Normal control cells were grown in full culture medium under normoxic conditions. Model control cells were treated with OGD/R (2 h OGD+24 h R). Therapeutic cells were incubated with nimodipine (10 μmol/L) or beta-asarone (20, 30, or 45 μg/mL) respectively for 3 h (1 h before OGD and 2 h OGD). They were incubated with full and drug-free culture medium for 24 h. β-asarone (20, 30, or 45 μg/mL) and nimodipine (10 μmol/L) both significantly increased cell viability and MMP in OGD/R treated cells. Mean±SD for 10 samples.

cP<0.01 vs normal control.

fP<0.01 vs OGD/R treated group.