Table 3. The effect of THP on cell cycle distribution of MG63/DOX cells. Mean±SD. n=3. bP<0.05, cP<0.01 compared with control.
| Action time | THP (ng/mL) | G0/G1 phase (%) | S phase (%) | G2/M phase (%) |
|---|---|---|---|---|
| 24 h | ||||
| 0 | 16.5±3.54 | 30.8±0.28 | 52.7±3.25 | |
| 50 | 17.4±2.56 | 29.5±0.85 | 53.1±1.69 | |
| 200 | 5.61±4.51 | 32.25±3.46 | 62.1±1.13b | |
| 500 | 12.78±11.01 | 9.6±13.58 | 77.65±2.47c | |
| 48 h | ||||
| 0 | 15.8±2.76 | 29.7±1.33 | 52.1±2.14 | |
| 50 | 20.9±1.015 | 23.47±2.8 | 55.63±1.79 | |
| 200 | 11±0.78 | 15.23±3.65 | 73.77±3.56c | |
| 500 | 6.68±1.98 | 6.45±1.52 | 86.88±2.27c | |
| 72 h | ||||
| 0 | 18.2±1.84 | 28.3±2.28 | 53.6±3.76 | |
| 50 | 20.6±4.01 | 15.66±1.52 | 63.74±3.35b | |
| 200 | 13.03±2.00 | 6.53±2.86 | 80.43±2.6c | |
| 500 | 2.72±0.77 | 3.07±2.7 | 94.2±3.41c | |