Table 1. Effect of heparin on activated partial thromboplastin time (APTT) and hemorheological parameters in Balb/c nude mice burdened with B16-F10-luc-G5 cells. Mean±SEM. n=5. ^cP<0.01 vs model.

Drug	Hematocrit (%)	Elongation Index		Orientation Index		Whole blood viscocity (mPa/s)		APTT (s)
		100/s	1000/s	100/s	1000/s	100/s	1000/s
Normal	39±3.99c	36.61±5.58c	66.9±4.16	8.2±0.74c	10.1±1.15c	7.77±0.64c	3.54±0.47c	28.6±4.35
Model	21±4.60	28.2±2.69	64.2±3.58	4.94±0.69	5.03±0.24	12.19±2.28	4.58±0.02	27.11±3.13
Heparin	44±4.55c	37.6±4.60c	65.6±4.80	8.54±0.83c	9.34±0.91c	8.06±0.13c	3.88±0.11c	29.02±4.08