Table 3. Thirty of the significantly decreased spots after heparin administration in lung tissue of Balb/c nude mice burdened with B16-F10-luc-G5 cells identified by Q-TOF analysis and search of the Mascot database.

Protein spot	Protein name	Mass	Score	Matches	Sequences	emPAI
1	Carbonyl reductase [NADPH]	26 056	335	15 (9)	7 (5)	1.32
2	14-3-3 protein zeta/delta	27 925	370	15 (11)	10 (7)	2.08
3	Hemoglobin subunit beta-1	15 944	79	1 (1)	1 (1)	0.21
4	Selenium-binding protein 1	53 051	72	4 (3)	3 (2)	0.13
5	Elongation factor 1-beta	24 849	344	5 (4)	3 (3)	0.46
6	Phosphoglycerate mutase 2	28 980	350	29 (21)	10 (8)	2.31
7	Carbonyl reductase [NADPH] 2	26 056	662	34 (23)	12 (7)	1.96
8	Troponin I, fast skeletal muscle	21 515	268	26 (15)	9 (5)	2.68
9	Hemoglobin subunit alpha	15 133	165	6 (6)	3 (3)	0.84
10	Carbonic anhydrase 3	29 633	144	31 (11)	8 (5)	1.34
11	Triosephosphate isomerase	32 684	65	25 (7)	10 (4)	0.47
12	Transcription factor BTF3	22 017	34	9 (1)	4 (1)	0.33
13	HIV Tat-specific factor 1 homolog	86 644	27	1 (0)	1 (0)	0.04
14	Transgelin	22 618	19	4 (0)	3 (0)	0.15
15	Filamin A-interacting protein 1-like	130 263	15	2 (0)	1 (0)	0.03
16	Monoglyceride lipase	33 708	64	13 (3)	7 (2)	0.46
17	Fructose-bisphosphate aldolase A	39 787	45	3 (1)	3 (1)	0.17
18	Creatine kinase M-type	43 246	36	25 (2)	10 (1)	0.16
19	Advanced glycosylation end product-specific receptor	42 984	19	2 (0)	1 (0)	0.08
20	Beta-enolase	47 337	31	9 (1)	8 (1)	0.07
21	Fatty acid-binding protein, epidermal	15 470	19	1 (1)	1 (1)	0.22
22	40S ribosomal protein SA	32 931	28	3 (1)	3 (1)	0.1
23	Myosin light chain 3	22 521	635	41 (30)	14 (11)	3.6
24	Serum albumin	70 700	302	25 (17)	12 (7)	0.44
25	Vimentin	53 712	24	1 (0)	1 (0)	0.06
26	Phosphoglycerate mutase 1	28 928	217	19 (11)	7 (4)	0.92
27	Adenylate kinase isoenzyme 1	21 640	49	21 (3)	8 (3)	0.78
28	Pyruvate dehydrogenase protein X component, mitochondrial	54 250	39	3 (2)	3 (2)	0.13
29	Myosin regulatory light chain 2, skeletal muscle isoform	19 057	44	18 (2)	4 (2)	0.38
30	Dynein heavy chain 12, axonemal	3 587 387	31	1 (1)	1 (1)	0.01