Table 2.

Associations between BCAR1 expression and clinical-demographical characteristics in NSCLC dataset

Variables	Analysis	Adenocarcinoma-mRNA Mayo Clinic dataset DASL(N=77)		Adenocarcinoma-mRNA TCGA dataset RNA-seq v2(N=288)		Squamous Carcinoma-mRNA TCGA dataset RNA-seq V2(N=220)		Adenocarcinoma-protein Daping Hospital IHC(N=75)		Squamous carcinoma-protein IHC(N=75)
		Valid Case (n)	BCAR1	Valid Case (n)	BCAR1	Valid Case (n)	BCAR1	Valid Case (n)	BCAR1 (Q score)	Valid Case (n)	BCAR1 (Q score)
Age	Pearson Correlation	77	0.047	268	-0.028	211	0.041	74	0.061	75	0.021
	P value		0.686		0.648		0.551		0.606		0.855
Gender#	Male	14	6.800±0.440	133	10.332±0.803	161	10.434±0.609	41	1.778±0.846	71	1.649±0.866
	Female	63	7.002±0.612	154	10.448±0.717	58	10.282±0.883	34	1.927±0.875	4	1.100±0.702
	P value				0.197		0.151		0.459		0.161
Smoking Status	Never-smoker	N.A.		36	10.331±1.054	10	10.540±0.653	N.A.
	Current or former smoker			239	10.395±0.707	203	10.392±0.694
	P value				0.989		0.509
Stage	Spearman's rho	77	0.400**	282	0.130*	216	0.011	75	0.170	75	0.121
	P value		<0.001		0.029		0.877		0.145		0.300
Lymphatic metastasis	No	52	6.825±0.521	171	10.327±0.794	141	10.363±0.713	34	1.603±0.846	44	1.594±0.898
	Yes	25	7.271±0.578	110	10.502±0.694	78	10.449±0.074	40	2.068±0.822	31	1.657±0.824
	P value		0.001**		0.052*		0.755		0.020*		0.761

Shaded variables are statistically different (P<0.05).

^**P value is significant at the 0.01 level (2-tailed).

^*P value is significant at the 0.05 level (2-tailed).

N.A. Not available