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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Mar 6;34(5):966–975. doi: 10.1161/ATVBAHA.113.302484

Figure 8. Mice deficient in GC-GR signaling in thymocytes/T cells are susceptible to CLP-induced septic death.

Figure 8

CLP (25G needle, full ligation) was performed on 8 to 10-week old lckCre-GRfl/fl and GRfl/fl littermates. After 18 h, the apoptotic thymocytes were analyzed with TUNEL staining using FACS (A and B), n = 6 each group. Survival was monitored for 7 days and analyzed with Log-Rank x2. lckCre-GRfl/fl (n = 13) and GRfl/fl (n = 8) littermates,