Figure 8. M1/M2 score of ACS patients.
(A–B) Percentage of patients classified according to the M1/M2 Score of UA (black bars), NSTEMI (dark gray bars) and STEMI (light grey bars) patients, calculated using mRNA expression levels of TNFα and IL10 in MΦs (see Methods). (A) At baseline: M1, M1/M0, M0, M0/M2, M2. (B) After LPS (3 h, 10 ng/ml): M1high, M1, M1/M2, M2. (C–D) Circulating mtDNA levels in the plasma of ACS patients compared with the M1/M2 score. Data are shown as Mean±SD. (C) Score at basal condition: M1 n = 2, M1/M0 n = 5, M0 n = 19, M0/M2 n = 28, M2 n = 21. (D) Score after LPS (3 h, 10 ng/ml): M1-high n = 5, M1 n = 27, M1/M2 n = 23, M2 n = 20.