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. Author manuscript; available in PMC: 2014 May 5.
Published in final edited form as: Vaccine. 2013 Jul 24;31(40):4314–4321. doi: 10.1016/j.vaccine.2013.07.025

Fig. 5.

Fig. 5

pWRG/SN-M(opt) DNA vaccine (gene gun) does not protect hamsters from ANDV challenge. A group of 8 hamsters received 3 vaccinations with pWRG/SNM(opt). (A) Vaccinated and unvaccinated hamsters were challenged with 200 PFU ANDV i.m. and observed for survival. (B) Sera collected prechallenge were tested by SNV PRNT for homotypic neutralizing antibodies. The PRNT limit of detection was a titer of 20 (dashed lines). *indicate antibody response was statistically significant when compared to no vaccine controls. s indicates the PRNT titer of a surviving hamster.