Figure 6. Effect of anti-LRP/LR specific antibody IgG1-iS18 on the adhesion of liver cancer (HUH-7) and leukaemia (K562) cells to laminin-1 determined through adhesion assays.

p-values shown in red (*p = 0.0238; ***p = 0.0002) are indicative of the increase in adhesive potential of liver cancer (HUH-7) and leukaemia (K562) cells in comparison to the breast cancer (MCF-7) control cell line. p-values shown in black (**p = 0.0031; ***p = 0.0005) represent the reduction in adhesive potential after treatment of cells with appropriate antibodies. A reduction of 63.35% in the adhesive potential was observed upon administration of IgG1-iS18 to the HUH-7 liver cancer cells. Data represents experiments performed in triplicate and repeated at least three times.