Table 3. Impact of the presence of asthma or mood and anxiety disorders at baseline on CD development as compared to those with a another CD at baseline that also developed CD.
Asthma | Mood and anxiety disorders | |||||||||
With asthma | Without ashtma | P | P adjusted for age and sex | P adjusted for other risk factor& | With mood and anxiety disorders | Without mood and anxiety disorder | P | P adjusted for age and sex | P adjusted for other risk factor& | |
n | 142 | 619 | 123 | 638 | ||||||
Number of CD developed (n(%)) | NS | NS | NS | <0.05 | <0.05 | <0.05 | ||||
1 | 80 (56) | 378 (61) | 62 (50) | 396 (62)* | ||||||
2 | 49 (34) | 165 (27) | 45 (37) | 169 (26)* | ||||||
3+ | 13 (10) | 76 (12) | 16 (13) | 73 (11) | ||||||
Individual CD developed§ | ||||||||||
Asthma | 37 (30) | 134 (21) | <0.05 | <0.05 | = 0.06 | |||||
COPD | 49 (35) | 140 (23) | <0.005 | <0.0001 | <0.001 | 23 (19) | 166 (26) | NS | NS | NS |
Mood and anxiety disorders | 29 (20) | 107 (17) | NS | NS | NS | |||||
Other mental disorders | 25 (18) | 94 (15) | NS | NS | NS | 44 (36) | 75 (12) | <0.0001 | <0.0001 | <0.0001 |
Hypercholesterolemia | 52 (37) | 129 (21) | <0.0001 | <0.0001 | <0.0001 | 37 (30) | 144 (23) | NS | NS | NS |
Diabetes | 13 (9) | 69 (11) | NS | NS | NS | 22 (18) | 60 (9) | <0.01 | <0.01 | <0.01 |
CVD+Stroke | 14 (10) | 45 (7) | NS | NS | NS | 8 (6) | 51 (8) | NS | NS | NS |
Hypertension | 37 (26) | 200 (32) | NS | NS | NS | 33 (27) | 204 (32) | NS | NS | NS |
*significantly different between individuals with either Asthma or Mood and anxiety disorders groups and the rest of the individuals in the progressive multimorbidity groups at baseline; NS: no significant difference;
Model adjusted for age, sex, BMI, marital status, education, income and working status at baseline,
The sum of this column is not 100% since some individuals developed more than one CD; CD: chronic disease; COPD: chronic obstructive pulmonary disease; and CVD = cardiovascular disease and stroke.