Skip to main content
. 2014 May 5;9(5):e96291. doi: 10.1371/journal.pone.0096291

Table 3. Impact of the presence of asthma or mood and anxiety disorders at baseline on CD development as compared to those with a another CD at baseline that also developed CD.

Asthma Mood and anxiety disorders
With asthma Without ashtma P P adjusted for age and sex P adjusted for other risk factor& With mood and anxiety disorders Without mood and anxiety disorder P P adjusted for age and sex P adjusted for other risk factor&
n 142 619 123 638
Number of CD developed (n(%)) NS NS NS <0.05 <0.05 <0.05
1 80 (56) 378 (61) 62 (50) 396 (62)*
2 49 (34) 165 (27) 45 (37) 169 (26)*
3+ 13 (10) 76 (12) 16 (13) 73 (11)
Individual CD developed§
Asthma 37 (30) 134 (21) <0.05 <0.05  = 0.06
COPD 49 (35) 140 (23) <0.005 <0.0001 <0.001 23 (19) 166 (26) NS NS NS
Mood and anxiety disorders 29 (20) 107 (17) NS NS NS
Other mental disorders 25 (18) 94 (15) NS NS NS 44 (36) 75 (12) <0.0001 <0.0001 <0.0001
Hypercholesterolemia 52 (37) 129 (21) <0.0001 <0.0001 <0.0001 37 (30) 144 (23) NS NS NS
Diabetes 13 (9) 69 (11) NS NS NS 22 (18) 60 (9) <0.01 <0.01 <0.01
CVD+Stroke 14 (10) 45 (7) NS NS NS 8 (6) 51 (8) NS NS NS
Hypertension 37 (26) 200 (32) NS NS NS 33 (27) 204 (32) NS NS NS

*significantly different between individuals with either Asthma or Mood and anxiety disorders groups and the rest of the individuals in the progressive multimorbidity groups at baseline; NS: no significant difference;

?

Model adjusted for age, sex, BMI, marital status, education, income and working status at baseline,

§

The sum of this column is not 100% since some individuals developed more than one CD; CD: chronic disease; COPD: chronic obstructive pulmonary disease; and CVD =  cardiovascular disease and stroke.