Table 1. pH, blood gases, glucose and lactate values at baseline, during and after umbilical cord occlusion.
| Baseline | 2 min | 12 min | +30 min | +1 h | +2 h | +3 h | +4 h | +6 h | +24 h | +48 h | +72 h | ||
| pH | S | 7.39±0.01 | 7.38±0.01 | 7.39±0.01 | 7.39±0.01 | 7.39±0.01 | 7.38±0.01 | 7.39±0.01 | 7.38±0.01 | 7.39±0.01 | 7.38±0.01 | 7.37±0.00 | 7.37±0.02 |
| O | 7.38±0.01 | 7.28±0.01§ | 6.92±0.01§ | 7.20±0.01§ | 7.24±0.02§ | 7.29±0.02* | 7.33±0.02 | 7.33±0.03 | 7.34±0.03 | 7.40±0.01 | 7.40±0.01§ | 7.39±0.01 | |
| pCO2 | S | 53.2±1.6 | 47.0±1.7 | 52.8±1.7 | 48.2±1.8 | 53.1±1.6 | 48.6±2.6 | 52.7±1.7 | 47.4±1.8 | 52.9±1.8 | 52.2±1.5 | 53.0±2.4 | 53.4±1.1 |
| (mmHg) | O | 52.8±1.4 | 63.0±1.9§ | 136.2±3.5§ | 50.2±1.3 | 54.0±1.2 | 48.0±1.0 | 51.7±1.2 | 47.8±1.0 | 51.9±1.5 | 49.9±1.1 | 49.8±1.4 | 51.6±1.2 |
| pO2 | S | 23.1±0.9 | 23.4±1.3 | 23.6±1.0 | 23.4±1.5 | 22.9±0.8 | 23.7±1.3 | 23.0±1.3 | 22.7±1.2 | 22.1±1.4 | 23.8±1.1 | 22.2±0.8 | 21.6±0.7 |
| (mmHg) | O | 22.4±0.9 | 6.7±0.6§ | 5.0±0.5§ | 28.0±1.1* | 25.3±1.2 | 24.1±1.3 | 22.2±1.2 | 22.1±1.1 | 21.1±1.3 | 21.5±1.1 | 25.6±1.1 | 26.2±1.1* |
| Hb | S | 10.6±0.3 | 9.7±0.1 | 10.4±0.3 | 10.1±0.1 | 10.4±0.3 | 9.7±0.2 | 10.4±0.3 | 9.6±0.3 | 10.2±0.3 | 9.7±0.3 | 9.8±0.5 | 10.2±0.3 |
| (g.dL−1) | O | 10.4±0.4 | 10.7±0.3 | 11.6±0.3* | 10.7±0.3 | 10.9±0.3 | 10.0±0.3 | 10.3±0.4 | 9.8±0.3 | 10.2±0.4 | 10.3±0.4 | 10.3±0.4 | 9.9±0.5 |
| Hct | S | 31.2±0.8 | 28.3±0.4 | 31.0±0.8 | 29.3±0.3 | 30.5±0.9 | 28.5±0.7 | 30.5±1.0 | 28.2±0.7 | 29.8±0.8 | 28.5±0.8 | 28.8±1.7 | 30.2±1.0 |
| O | 30.6±1.1 | 31.5±1.0 | 33.9±1.0 | 31.4±0.9 | 32.0±1.0 | 29.4±1.0 | 30.4±1.1 | 28.9±0.9 | 30.0±1.0 | 30.5±1.2 | 30.2±1.2 | 29.3±1.4 | |
| O2ct | S | 4.4±0.3 | 4.0±0.2 | 4.4±0.2 | 4.1±0.3 | 4.2±0.2 | 4.1±0.2 | 4.3±0.3 | 3.8±0.2 | 4.2±0.3 | 4.1±0.2 | 3.8±0.2 | 3.9±0.3 |
| (mmol.L−1) | O | 4.1±0.2 | 0.5±0.0§ | 0.5±0.0§ | 4.2±0.2 | 4.1±0.2 | 3.6±0.2 | 3.7±0.3 | 3.5±0.2 | 3.5±0.3 | 3.7±0.2 | 4.4±0.2 | 4.3±0.2 |
| HCO3− | S | 29.2±1.0 | 25.8±1.0 | 29.2±0.9 | 26.9±1.2 | 29.1±0.8 | 26.2±1.2 | 28.7±1.1 | 26.0±1.1 | 29.2±1.1 | 28.2±1.0 | 27.9±1.1 | 28.2±1.2 |
| (mmol.L−1) | O | 28.5±0.5 | 24.5±0.5 | 17.5±1.5§ | 17.2±0.3§ | 19.7±0.5§ | 20.6±0.8§ | 24.4±1.1* | 23.5±1.4 | 25.4±1.6 | 28.5±1.0 | 28.9±0.6 | 28.7±0.4 |
| BE | S | 5.5±1.1 | 1.9±1.1 | 5.5±1.0 | 3.0±1.4 | 5.3±0.8 | 2.3±1.4 | 5.0±1.2 | 2.1±1.3 | 5.5±1.2 | 4.3±1.1 | 4.0±1.3 | 4.3±1.7 |
| (mmol.L−1) | O | 4.5±0.5 | 0.9±0.5 | −8.4±0.4§ | −8.8±0.4§ | −5.6±0.6§ | −4.2±1.0§ | 0.0±1.4 | −1.0±1.8 | 1.2±1.8 | 4.8±1.1 | 5.0±0.5 | 5.0±0.3 |
| Lactate | S | 1.1±0.1 | 1.0±0.1 | 1.1±0.1 | 1.1±0.1 | 1.2±0.1 | 1.1±0.1 | 1.3±0.2 | 1.2±0.1 | 1.2±0.2 | 1.2±0.1 | 1.3±0.1 | 1.1±0.1 |
| (mmol.L−1) | O | 1.1±0.1 | 1.6±0.1§ | 6.0±0.3§ | 5.8±0.2§ | 6.5±0.3§ | 5.6±0.5§ | 5.3±0.6§ | 5.3±0.9* | 5.8±1.3* | 3.2±0.8 | 1.3±0.1 | 1.1±0.1 |
| Glucose | S | 1.0±0.1 | 0.8±0.1 | 0.9±0.1 | 0.9±0.0 | 1.0±0.1 | 0.9±0.0 | 1.0±0.1 | 0.9±0.1 | 0.9±0.1 | 0.8±0.1 | 0.8±0.1 | 0.8±0.1 |
| (mmol.L−1) | O | 0.8±0.1 | 0.5±0.0§ | 1.0±0.1 | 1.7±0.2* | 1.6±0.1* | 1.2±0.1* | 1.3±0.1* | 1.2±0.1* | 1.5±0.1§ | 1.5±0.1§ | 1.4±0.1* | 1.0±0.1 |
S: sham occlusion. O: umbilical cord occlusion. Hb: haemoglobin concentration; Hct: hematocrit; O2ct: oxygen concentration; HCO3 −: bicarbonate; BE: base excess.
*p<0.05;
§
p<0.005 compared to sham occlusion group. Data are mean±SEM.